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己酮可可碱治疗闭塞性脑血管疾病的临床经验。

Clinical experience with pentoxifylline in occlusive cerebrovascular disorders.

作者信息

Sen S, Chakravarty A

出版信息

Angiology. 1977 May;28(5):340-5. doi: 10.1177/000331977702800505.

DOI:10.1177/000331977702800505
PMID:869291
Abstract

Pentoxifylline--3,7-dimethyl-1(5-oxo-hexyl) xanthine--a new vasodilator compound, was tried in 28 cases of occlusive cerebrovascular disease. A similar group of 24 patients were given xanthinol nicotinate. Although in terms of degree of improvement there was no significant difference in the two treatment groups, improvement was earlier in the group treated with pentoxifylline. No significant side effects were observed with any of the two drugs used in the present study.

摘要

己酮可可碱——3,7 - 二甲基 - 1(5 - 氧代己基)黄嘌呤——一种新型血管扩张剂化合物,在28例闭塞性脑血管疾病患者中进行了试验。另外一组24例患者给予烟胺羟丙茶碱。虽然在改善程度方面,两个治疗组没有显著差异,但己酮可可碱治疗组的改善出现得更早。本研究中使用的两种药物均未观察到明显的副作用。

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Clinical experience with pentoxifylline in occlusive cerebrovascular disorders.己酮可可碱治疗闭塞性脑血管疾病的临床经验。
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Pentoxifylline in strokes: a clinical study.
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[Clinical study of the cerebrovascular action of pentoxifylline].[己酮可可碱对脑血管作用的临床研究]
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The treatment of chronic cerebrovascular insufficiency. A double-blind study with pentoxifylline ('Trental' 400).慢性脑血管供血不足的治疗。己酮可可碱(“曲克芦丁”400)双盲研究。
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[A preliminary report of treatment of transient cerebral ischemic attacks with BL 191 (author's transl)].
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[5 years of clinico-experimental and therapeutic experiences with pentoxifylline].己酮可可碱的5年临床实验与治疗经验
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Pentoxifylline. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy.己酮可可碱。对其药效学和药代动力学特性以及治疗效果的综述。
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Effect of pentoxifylline on decreased in vitro mononuclear leucocyte chemotaxis in vascular and polysystemic autoimmune diseases.
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Agents Actions. 1991 Jul;33(3-4):254-9. doi: 10.1007/BF01986571.