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己酮可可碱治疗闭塞性脑血管疾病的临床经验。

Clinical experience with pentoxifylline in occlusive cerebrovascular disorders.

作者信息

Sen S, Chakravarty A

出版信息

Angiology. 1977 May;28(5):340-5. doi: 10.1177/000331977702800505.

Abstract

Pentoxifylline--3,7-dimethyl-1(5-oxo-hexyl) xanthine--a new vasodilator compound, was tried in 28 cases of occlusive cerebrovascular disease. A similar group of 24 patients were given xanthinol nicotinate. Although in terms of degree of improvement there was no significant difference in the two treatment groups, improvement was earlier in the group treated with pentoxifylline. No significant side effects were observed with any of the two drugs used in the present study.

摘要

己酮可可碱——3,7 - 二甲基 - 1(5 - 氧代己基)黄嘌呤——一种新型血管扩张剂化合物,在28例闭塞性脑血管疾病患者中进行了试验。另外一组24例患者给予烟胺羟丙茶碱。虽然在改善程度方面,两个治疗组没有显著差异,但己酮可可碱治疗组的改善出现得更早。本研究中使用的两种药物均未观察到明显的副作用。

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