嗜酸性粒细胞增多性多发性血栓形成。关于播散性嗜酸性“胶原病”新命名的提议。

Hypereosinophilic multiple thrombosis. A proposal of a new designation of disseminated eosinophilic "collagen disease".

作者信息

Ishii T, Koide O, Hosoda Y, Takahashi R

出版信息

Angiology. 1977 Jun;28(6):361-75. doi: 10.1177/000331977702800601.

DOI:10.1177/000331977702800601

Abstract

A case of marked chronic mature eosinophilia associated with multiple thrombosis in 30-year-old male is presented. Hitherto this sort of the disease has been categorized as DECD. Reviewing the autopsied cases of DECD, including our own case, DECD should not be categorized as a collagen disease because of the absent connective tissue degeneration and absent connective tissue degeneration and absent serological abnormalities. We rather noticed a certain relation between marked chronic mature eosinophilia and thrombus formation. Therefore, we propose here the term hypereosinophilic multiple thrombosis to express the pathomorphogenesis more precisely.

摘要

本文报告一例30岁男性患者，其患有显著的慢性成熟嗜酸性粒细胞增多症并伴有多处血栓形成。迄今为止，这类疾病被归类为弥漫性结缔组织病（DECD）。回顾包括我们自己病例在内的DECD尸检病例，由于不存在结缔组织变性和血清学异常，DECD不应被归类为胶原病。我们反而注意到显著的慢性成熟嗜酸性粒细胞增多症与血栓形成之间存在某种关联。因此，我们在此提出“嗜酸性粒细胞增多性多发性血栓形成”这一术语，以更准确地表达病理形态发生过程。