Jelcić A, Delimar D
Poliklinika za reumatske bolesti, fizikalnu medicinu i rehabilitaciju Zagreb.
Reumatizam. 1995;42(1):1-5.
The trial included 641 subjects, 200 (31.2%) of whom were found to have hand arthrosis. There were 135 (33.1%) women and 65 (27.9%) men with an average age of 54 (ranging from 35 to 75 years). Interphalangeal arthrosis was found in 33.1% of women and 25.8% of men, and rhisarthrosis in 8.3% of women and 7.3% of men. No significant differences in sex and age was found between these two groups of subjects (P = 0.45, P = 0.70). The relative incidence of arthrosis of the right hand was slightly higher than that of the left hand, but this difference was not significant because it was below 5% and 3.7%, respectively. Distal interphalangeal joints were more than three times more frequently affected than proximal interphalangeal joints. Pain and functional inability were found in two thirds of patients with rhisarthrosis and in one third of patients with interphalangeal arthrosis, and were closely correlated with the menopause. A significant correlation was found between the onset of menopause and clinical symptoms (r = 0.87, P = < 0.001).
该试验纳入了641名受试者,其中200名(31.2%)被发现患有手部关节病。有135名(33.1%)女性和65名(27.9%)男性,平均年龄为54岁(年龄范围为35至75岁)。指间关节病在33.1%的女性和25.8%的男性中被发现,桡腕关节病在8.3%的女性和7.3%的男性中被发现。这两组受试者在性别和年龄方面未发现显著差异(P = 0.45,P = 0.70)。右手关节病的相对发病率略高于左手,但由于分别低于5%和3.7%,这种差异不显著。远端指间关节受累的频率比近端指间关节高出三倍多。桡腕关节病患者中有三分之二以及指间关节病患者中有三分之一出现疼痛和功能障碍,且与绝经密切相关。绝经 onset与临床症状之间存在显著相关性(r = 0.87,P = < 0.001)。 (注:原文中“menopause onset”翻译为“绝经onset”,这里“onset”直接保留英文,因为不清楚其在原文中的准确中文表述,推测可能是想表达“绝经起始”之类的意思,但按照要求不添加解释,所以保留英文供你参考。)