Jajić Z, Jajić I, Grazio S
Klinika za fizikalnu medicinu, rehabilitaciju i reumatologiju Klinicka bolnica Sestre milosrdnice, Zagreb.
Reumatizam. 1995;42(2):7-9.
In 30 patients (20 males and 10 females) wih psoriatic arthritis chloroquine was administered in a dosage of 250 mg daily per os. After 12 months of monitoring decreased number of swollen and painfully tender joints were found as well as shortening in duration of morning stiffness. As for laboratory parameters lowering of the average values of ESR and alpha-2 globulins were found whilst there were no changes of ceruloplasmin, haptoglobin and CRP. Worsening of skin lesions was observed in only 2 patients (6.5%). These results suggest that synthetic antimalarials (chloroquine) can be successfully used in the treatment of psoriatic arthritis with special care.
在30例银屑病关节炎患者（20例男性和10例女性）中，口服氯喹，剂量为每日250毫克。经过12个月的监测，发现肿胀和压痛关节的数量减少，晨僵持续时间缩短。至于实验室参数，发现血沉和α-2球蛋白的平均值降低，而铜蓝蛋白、触珠蛋白和CRP没有变化。仅2例患者（6.5%）出现皮肤病变恶化。这些结果表明，合成抗疟药（氯喹）可在特别护理下成功用于治疗银屑病关节炎。
