Binek J, Morant R, Weber A, Schmid U, Hammer B
Abteilung für Gastroenterologie, Kantonsspital, St. Gallen.
Schweiz Med Wochenschr. 1996 May 11;126(19):841-4.
From January 1 1994 to March 1 1995 we observed 6 patients with gastric low-grade B-cell lymphoma of MALT type in association with Helicobacter pylori infection. Endoscopically only 3 of the 6 patients presented with pathological findings. All but one patient with metastatic carcinoma received antibiotic therapy for Helicobacter pylori. Follow-up was not possible in one patient who died unexpectedly. In all 4 patients followed-up, eradication of Helicobacter pylori resulted in regression of the malignant lymphoma. During the median follow-up time of 7 months (2-13 months) no relapse of lymphoma was observed. Our results confirm that gastric low-grade B-cell lymphoma of MALT type can regress after eradication of Helicobacter pylori.
1994年1月1日至1995年3月1日期间,我们观察了6例与幽门螺杆菌感染相关的胃MALT型低度B细胞淋巴瘤患者。内镜检查发现,6例患者中只有3例有病理表现。除1例转移性癌患者外,所有患者均接受了针对幽门螺杆菌的抗生素治疗。1例意外死亡患者无法进行随访。在所有接受随访的4例患者中,幽门螺杆菌根除后恶性淋巴瘤消退。在中位随访时间7个月(2 - 13个月)内,未观察到淋巴瘤复发。我们的结果证实,根除幽门螺杆菌后,胃MALT型低度B细胞淋巴瘤可消退。