Laudat A, Ano-Monfils N, Haddad A, Pileire B
Laboratoire de Biochimie et Service de Cardiologie, Centre Hospitalier Régional Universitaire, Guadeloupe.
West Indian Med J. 1996 Mar;45(1):28-30.
Plasma fibronectin (Fbn) was assessed daily in 9 men admitted to the cardiology care unit for uncomplicated acute myocardial infarction (AMI). In a control group of twenty healthy men, plasma Fbn was 0.290 +/- 0.0417 g/l-1 (mean +/- SD). In 6 hypertensive AMI patients, Fbn levels were increased to a maximum of 0.461 +/- 0.0294 g/l-1 at day five (5.5 +/- 0.84 days) and returned to the range of the control group values 56 +/- 32.8 hours afterwards. Three normotensive patients had higher Fbn results without returning to the control group range at the end of the hospitalization (0.734 +/- 0.0209 gl-1). Plasma Fbn could in part be implicated in the repair process and/or in the limitation of the cardiac necrosis extension. Moreover, it seems that a link exists between plasma Fbn kinetics and hypertension and/or normotension during uncomplicated AMI.
对9名因无并发症急性心肌梗死（AMI）入住心脏病监护病房的男性患者，每日评估血浆纤维连接蛋白（Fbn）。在20名健康男性组成的对照组中，血浆Fbn为0.290±0.0417 g/l-1（均值±标准差）。6名高血压AMI患者中，Fbn水平在第5天（5.5±0.84天）最高升至0.461±0.0294 g/l-1，之后56±32.8小时恢复至对照组值范围。3名血压正常的患者Fbn结果较高，住院结束时未恢复至对照组范围（0.734±0.0209 gl-1）。血浆Fbn可能部分参与修复过程和/或限制心脏坏死扩展。此外，在无并发症AMI期间，血浆Fbn动力学与高血压和/或血压正常之间似乎存在关联。
