Amblard P, Lèques B, Seigneurin D, Verdaguer S, Reymond J L
Ann Dermatol Venereol. 1977 Feb;104(2):115-20.
By the study of 4 personal cases and a review of the literature, the authors describe the symptoms which may complicate and even reveal an essential thrombocythemia. They are: painful symptoms which indicate a permanent or paroxystic vasculomotor syndrome by their localization and their course: -erythematous lesions of an inflammatory livedo type located on the legs and blue-red reticular spots on the sole of the foot: --occurrence of gangrene on finger ends or of necrotic ulcerations of the legs. Etiological conditions, exploration of primary hemostasis, physiopathology of the troubles are described. As for therapeutics the antiaggregants have a suspensive effect on the symptoms but only the control of the hematological status may allow recovery.
通过对4例个人病例的研究及文献回顾，作者描述了可能使原发性血小板增多症复杂化甚至揭示该病症的症状。这些症状包括：根据其部位和病程提示持续性或发作性血管舒缩综合征的疼痛症状；腿部出现炎症性青斑样红斑病变以及脚底出现蓝红色网状斑点；手指末端发生坏疽或腿部出现坏死性溃疡。文中还描述了病因、原发性止血的检查以及这些病症的病理生理学。至于治疗方法，抗聚集剂对症状有缓解作用，但只有控制血液学状态才能实现康复。
