Rodat O
Sem Hop. 1979;55(3-4):173-7.
The author relates the disease of a man with a digital necrotizing in keeping with an excess of platelets. Clinical, biological and histological study may evolve diagnosis of idiopathic thrombocythemia. The check of concerned literature may specify profile of this disease which agree with platelet side of a myeloproliferative syndrome. Coagulation study is often disappointing but may involve interference of prostaglandins as an intimate mechanism for aggregation and adhesivity of platelets. Clinical course may very easily be supervised with standard medical treatment.
作者讲述了一名患有与血小板过多相关的手指坏死的男子的病情。临床、生物学和组织学研究可能会改进特发性血小板增多症的诊断。查阅相关文献可以明确这种疾病的特征,它与骨髓增殖综合征的血小板方面相符。凝血研究常常令人失望,但可能涉及前列腺素的干扰,这是血小板聚集和黏附的内在机制。通过标准医疗治疗,临床病程很容易得到监测。