Laugier P, Hunziker N, Olmos L
Ann Dermatol Venereol. 1977 Mar;104(3):181-4.
Lenticular or linear, buccal or labial, slate-coloured or melanic black spots are noticed in healthy subjects with no racial, hormonal or drug factor. Histological examination shows a pigmentary excess of the basement membrane without anomaly or dystrophy or nevus cells. Ultrastructural study shows a great number of intracyto-plasmic melanosomes, isolated or in group in all the keratinocytes in the third inferior part of the epidermis. No explanation can be given to this melanocyte hyperactivity. An excision can be done without danger for esthetical purpose.
在没有种族、激素或药物因素的健康受试者中，可发现豆状或线状、颊部或唇部、石板色或黑色素黑色斑点。组织学检查显示基底膜色素沉着过多，无异常、营养不良或痣细胞。超微结构研究显示，在表皮下部第三层的所有角质形成细胞中，有大量孤立或成群的胞浆内黑素小体。无法对这种黑素细胞活性过高作出解释。出于美观目的，可以进行切除，且无危险。
