Moreno A, Rodriguez J M, Sola J, Soria T, Parrilla P
Departments of Surgery, Virgen de la Arrixaca University Hospital, Murcia, Spain.
Eur J Surg. 1996 Mar;162(3):177-80.
To study the clinical course of patients with the encapsulated variant of papillary thyroid carcinoma, in which there is a well-defined fibrous wall completely separating the tumour cells from the adjacent tissue.
Retrospective review.
University hospital, Spain.
Of a total of 163 patients whose papillary thyroid carcinomas were treated surgically between 1975 and 1985, there were 25 encapsulated tumours.
Clinicopathological features and survival rate compared with those of non-encapsulated papillary thyroid carcinomas.
Mean follow up was 9 years (range 7-17), and 42 were excluded because follow up was incomplete. Encapsulated tumours differed from the earlier age of other types in that they presented earlier (mean age 36 years compared with 45), they were significantly less likely to have symptoms of compression (1/25 compared with 24/96, p = 0.024), or nodal metastases (3/25 compared with 43/96, p = 0.002), or to recur (0/25 compared with 33/96, p = 0.002). No patients died in the encapsulated group compared with 11/96 in the other group.
Encapsulated papillary carcinomas have an excellent prognosis, and can be cured by operation.
研究甲状腺乳头状癌包膜型患者的临床病程，该型具有明确的纤维壁，可将肿瘤细胞与相邻组织完全分隔开。
回顾性研究。
西班牙大学医院。
1975年至1985年间接受手术治疗的163例甲状腺乳头状癌患者中，有25例为包膜型肿瘤。
与非包膜型甲状腺乳头状癌相比的临床病理特征和生存率。
平均随访9年（范围7 - 17年），42例因随访不完整被排除。包膜型肿瘤与其他类型相比发病年龄较早，表现为就诊较早（平均年龄36岁，其他类型为45岁），出现压迫症状的可能性显著较低（1/25比24/96，p = 0.024），发生淋巴结转移的可能性较低（3/25比43/96，p = 0.002），复发可能性也较低（0/25比33/96，p = 0.002）。包膜型组无患者死亡，其他组为11/96。
包膜型乳头状癌预后极佳，可通过手术治愈。
