Rodriguez J M, Moreno A, Parrilla P, Sola J, Soria T, Tebar F J, Aranda F
Department of Surgery, Virgen de la Arrixaca University Hospital, Murcia, Spain.
Eur J Surg. 1997 Apr;163(4):255-9.
To study the anatomical and prognostic characteristics of papillary thyroid microcarcinomas (10 mm or less in size).
Retrospective review.
Community hospital, Spain.
36 patients with papillary microcarcinomas diagnosed over a period of 20 years from a total of 158 papillary carcinomas with complete follow-up.
Symptoms, treatment, histopathological confirmation and follow-up compared with those of papillary carcinomas more than 10 mm in size.
Six of the patients with microcarcinomas presented with adenopathy, the remaining 30 being admitted for treatment of associated thyroid diseases. In 15 cases the tumour was 5 mm or less in size. Thirty were well-differentiated, 2 were follicular, and 2 showed signs of diffuse sclerosis. Three had recurred after total thyroidectomy, but no patient died. When the results were compared with those of the patients with larger tumours, we found differences in histological type (p = 0.001), the incidence of adenopathy (p = 0.03), TNM stage (p = 0.001) and mortality (p = 0.04).
There are clinical, histopathological, and prognostic differences between microcarcinomas (which do well) and larger papillary tumours.
研究甲状腺微小癌（大小为10毫米或更小）的解剖学和预后特征。
回顾性研究。
西班牙的社区医院。
在20年期间诊断出的36例微小癌患者，来自总共158例有完整随访资料的乳头状癌患者。
与大小超过10毫米的乳头状癌相比，微小癌的症状、治疗、组织病理学确诊情况及随访情况。
6例微小癌患者出现腺病，其余30例因相关甲状腺疾病入院治疗。15例肿瘤大小为5毫米或更小。30例为高分化，2例为滤泡状，2例有弥漫性硬化迹象。3例在全甲状腺切除术后复发，但无患者死亡。当将结果与较大肿瘤患者的结果进行比较时，我们发现组织学类型（p = 0.001）、腺病发生率（p = 0.03）、TNM分期（p = 0.001）和死亡率（p = 0.04）存在差异。
微小癌（预后良好）与较大的乳头状肿瘤在临床、组织病理学和预后方面存在差异。
