海刀豆叶片中脱镁叶绿酸a及其相关化合物作为潜在抗肿瘤促进剂的鉴定。

Identification of pheophorbide a and its related compounds as possible anti-tumor promoters in the leaves of Neptunia oleracea.

作者信息

Nakamura Y, Murakami A, Koshimizu K, Ohigashi H

机构信息

Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, Japan.

出版信息

Biosci Biotechnol Biochem. 1996 Jun;60(6):1028-30. doi: 10.1271/bbb.60.1028.

DOI:10.1271/bbb.60.1028

PMID:8695903

Abstract

Six chlorophyll-related compounds isolated from leaves of Neptunia oleracea (Leguminosae) inhibited the activation of tumor promoter-induced Epstein-Barr virus (EBV). Photo-irradiation of pheophorbide a, the major active constituent, did not enhance this inhibitory activity, and thus ruled out any photosensitizing effect playing the major role.

摘要

从 Neptunia oleracea（豆科）叶片中分离出的六种叶绿素相关化合物抑制了肿瘤启动子诱导的爱泼斯坦 - 巴尔病毒（EBV）的激活。主要活性成分脱镁叶绿酸 a 的光照射并未增强这种抑制活性，因此排除了任何起主要作用的光敏效应。