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[低迁移性钚-239进入大鼠呼吸器官后气管支气管淋巴结淋巴组织的状态]

[State of the lymphoid tissue of tracheobronchial lymph nodes in rats after incorporation in respiratory organs of low-transportable Pu-239].

作者信息

Sokol'nikov M E

出版信息

Radiats Biol Radioecol. 1996 Jan-Feb;36(1):133-8.

PMID:8696478
Abstract

After single inhalation exposure of rats to low transportable 239Pu the alpha-irradiation doses in tracheo-bronchial lymph nodes (TBLN) were one order of magnitude lower than those in lung. The reduction of cell population in TBLN was observed in late (12-18 month after) post-inhalation period. Dose-response curve for the reduction (as a whole for 12 month) were presented as a line function. Functional abilities of these cells were less damaged and observed in different periods after inhalation. As one of the probable mechanisms of different radiation damage to cells in TBLN population, a variety in their spatial distribution is discussed.

摘要

大鼠单次吸入低迁移性239Pu后,气管支气管淋巴结(TBLN)中的α辐射剂量比肺部低一个数量级。在吸入后期(吸入后12 - 18个月)观察到TBLN中细胞数量减少。减少量的剂量反应曲线(整个12个月期间)呈现为线性函数。这些细胞的功能能力受损较小,且在吸入后的不同时期都可观察到。作为TBLN群体中细胞受到不同辐射损伤的一种可能机制,讨论了它们空间分布的差异。

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