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放射防护与淋巴系统:气管支气管淋巴结及胃肠道壁内照射后白血病的诱发

Radiological protection and the lymphatic system: the induction of leukaemia consequent upon the internal irradiation of the tracheobronchial lymph nodes and the gastrointestinal tract wall.

作者信息

Baverstock K F, Thorne M C

机构信息

MRC Radiobiology Unit, Chilton, Oxon, U.K.

出版信息

Int J Radiat Biol. 1989 Jan;55(1):129-40. doi: 10.1080/09553008914550131.

DOI:10.1080/09553008914550131
PMID:2562969
Abstract

The excess of leukaemia among young people living in the vicinity of the nuclear fuel reprocessing plant at Sellafield has focused attention on the possibility that irradiation of the lymphatic system from particulate alpha-emitting nuclides might be responsible. We discuss below two possible routes of such exposure; namely the inhalation and ingestion of particulates. We conclude that, in spite of the real possibility of substantial doses to tissues associated with the lymphatic system, there is little reason to expect that lymphatic leukaemia will be the dominant outcome of the exposure. However, the arguments presented are not, and cannot be, wholly conclusive.

摘要

生活在塞拉菲尔德核燃料后处理厂附近的年轻人中白血病病例过多,这使得人们将注意力集中在一个可能性上,即来自发射α粒子的微粒对淋巴系统的辐射可能是病因。我们在下面讨论两种可能的暴露途径,即微粒的吸入和摄入。我们的结论是,尽管确实有可能使与淋巴系统相关的组织受到大量辐射,但几乎没有理由预期淋巴性白血病会成为这种暴露的主要后果。然而,所提出的论据并不完全确凿,也不可能完全确凿。

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