Feng B, Lang J, Li D
Peking Union Medical College Hospital, Beijing.
Zhonghua Yi Xue Za Zhi. 1995 Oct;75(10):614-6, 640.
We established a more suitable methodology for preparing liposomal adriamycin (Lipo-ADM) by a remote loading technique. This procedure is convenient, simple with an entrapment efficiency of 95%. The mean diameter of liposome is about 100nm showing unilamellar spherical shape. The leakage ratio is about 10% within 24hr. Those characteristics fit for clinical demand.
我们通过远程载入技术建立了一种更合适的制备脂质体阿霉素(Lipo - ADM)的方法。该过程简便易行,包封率达95%。脂质体的平均直径约为100nm,呈单层球形。24小时内泄漏率约为10%。这些特性符合临床需求。