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[通过脂多糖、肿瘤坏死因子和内皮素水平变化评判磺胺嘧啶银-磺胺嘧啶锌-氮酮乳膏、负离子照射及“湿润烧伤膏”预防烧伤创面感染的效果评估]

[Assessment of effectiveness of AgSD-ZnSD-Azone cream, negative ion irradiation and "moisture burn ointment" in prevention of burn wound infection as judged by changes in LPS, TNF and ET levels].

作者信息

Sun S, Guo Z, Yang H

机构信息

304th Hospital of People's, Liberation Army, Beijing.

出版信息

Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi. 1995 Sep;11(5):332-4.

PMID:8697244
Abstract

40 Wistar rats were scalded resulting in 15% TBSA full-thickness burn. Pseudomonas aeruginosa (10(9)/ml) was seeded on the wounds. The animals were divided into 4 groups. AgSD and ZnSD (with Azone) cream was applied to the wounds in the group I. The wounds were irradiated with negative ion current in the group II. The "moisture burn ointment" was applied to the wounds in the group III. Group IV consisted of controls without any treatment. Judging by changes in levels of LPS, TNF and ET, it was shown that the best result was obtained in the group I and II. The "moisture burn ointment" group yielded the poorest results.

摘要

将40只Wistar大鼠烫伤,造成15%体表面积的全层烧伤。将铜绿假单胞菌(10⁹/ml)接种于伤口。动物被分为4组。第一组在伤口上涂抹含氮酮的磺胺嘧啶银(AgSD)和磺胺嘧啶锌(ZnSD)乳膏。第二组用负离子电流照射伤口。第三组在伤口上涂抹“湿润烧伤膏”。第四组为未作任何处理的对照组。从脂多糖(LPS)、肿瘤坏死因子(TNF)和内皮素(ET)水平的变化来看,结果显示第一组和第二组效果最佳。“湿润烧伤膏”组效果最差。

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