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[不同局部用药对烧伤创面铜绿假单胞菌感染的影响]

[The effect of different topical agents on pseudomonas infection of burn wound].

作者信息

Guo Z, Gao W, He L

机构信息

304th Hospital, Beijing.

出版信息

Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi. 1995 Nov;11(6):421-4.

PMID:8728928
Abstract

48 Wistar rats were scalded resulting in 15% TBSA full-thickness burn. Pseudomonas aeruginosa (10(9)/ml was inoculated to the wounds. The rats were divided into 6 groups. 5 different topical agents were separately applied to the wounds constituting 5 groups, and no drug was used in control group. Through observing the appearance of wound, the quantity of bacteria in the subeschar tissue and histo-pathological changes, we confirmed that AgSD-ZnSD-A cream was a satisfactory topical agent.

摘要

48只Wistar大鼠被烫伤,造成15%体表面积的全层烧伤。将铜绿假单胞菌(10⁹/ml)接种于创面。大鼠被分为6组。5种不同的外用药物分别应用于创面,构成5个组,对照组不使用药物。通过观察创面外观、焦痂下组织细菌数量及组织病理学变化,我们证实磺胺嘧啶银-磺胺嘧啶锌乳膏是一种令人满意的外用药物。

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