Kelsey P R, Patel K
Department of Clinical Haematology, Victoria Hospital, Blackpool, UK.
Clin Lab Haematol. 1995 Dec;17(4):349-51.
We describe a patient with essential thrombocythaemia who developed multiple myeloma 7 years after an initial diagnosis of essential thrombocythaemia. A 50-year-old white female presented in 1987 with a 2 year history of low backache, painful swollen ankles and burning feet. Her laboratory investigations suggested a diagnosis of essential thrombocythaemia. Initially she was treated with busulphan without much benefit for 6 months. Subsequently she was treated with hydroxyurea with significant relief of her symptoms and reduction in her platelet count. Seven years after her initial presentation she developed bone pains and anaemia with laboratory investigations confirming a diagnosis of multiple myeloma.
我们描述了一名原发性血小板增多症患者，该患者在原发性血小板增多症初诊7年后发展为多发性骨髓瘤。一名50岁的白人女性于1987年就诊，有2年的腰痛、脚踝肿痛和足部烧灼感病史。她的实验室检查提示原发性血小板增多症的诊断。最初她接受白消安治疗6个月，效果不佳。随后她接受羟基脲治疗，症状明显缓解，血小板计数下降。初次就诊7年后，她出现骨痛和贫血，实验室检查确诊为多发性骨髓瘤。
