Gillinov A M, Greene P S, Stuart R S, Heitmiller R F
Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Chest. 1996 Aug;110(2):571-4. doi: 10.1378/chest.110.2.571.
Although performance of concomitant open heart and pulmonary operations has been described, there is general reluctance to perform pulmonary procedures in patients receiving cardiopulmonary bypass (CPB). Reasons for this include fear of excess bleeding caused by systemic heparinization, limited exposure afforded by median sternolomy, and alterations in the immune system caused by CPB that might lead to dissemination of lung cancer or infection. We have used CPB to facilitate operations on the lung in four patients who did not require concomitant cardiac surgery. In each case, lesions involving central pulmonary vessels precluded safe operation by conventional techniques. There were no complications related to the use of CPB. We believe that CPB can be a valuable adjunct in the surgical treatment of selected tumors and vascular malformations that involve large or central pulmonary vessels.
尽管已经有人描述了同期进行心脏直视手术和肺部手术的情况,但对于接受体外循环(CPB)的患者进行肺部手术,人们普遍存在顾虑。这样做的原因包括担心全身肝素化导致出血过多、正中胸骨切开术提供的暴露有限,以及CPB引起的免疫系统改变可能导致肺癌扩散或感染。我们对4例不需要同期进行心脏手术的患者使用CPB来辅助肺部手术。在每例病例中,累及中央肺血管的病变使得传统技术无法安全进行手术。未出现与使用CPB相关的并发症。我们认为,对于涉及大的或中央肺血管的特定肿瘤和血管畸形,CPB可以成为手术治疗中的一项有价值的辅助手段。