Olson L D
Avian Dis. 1977 Apr-Jun;21(2):160-6.
The pulmonary form of experimentally induced fowl cholera was controlled effectively either by Rofenaid, a potentiated sulfadimethoxine, at 0.01% in feed, chlortetracycline at 0.0055% in feed, vaccination with a commercial fowl cholera bacterin and a combination of Rofenaid and vaccination. The medicated or/and vaccinated turkeys had a significantly (P less than 0.05) better livability than the unmedicated or unvaccinated exposed turkeys. Turkeys were exposed by contact with carriers and administration of Pasteurella multocida in drinking water. Transmission from carriers to recipients through the water was demonstrated. P. multocida was isolated from the mouths of recipient turkeys receiving low-level medication one week after carriers were introduced.
通过在饲料中添加0.01%的增效磺胺二甲氧嘧啶(Rofenaid)、在饲料中添加0.0055%的金霉素、使用商用禽霍乱菌苗进行疫苗接种以及Rofenaid与疫苗接种相结合的方式,可有效控制实验性诱发禽霍乱的肺部感染形式。用药或/和接种疫苗的火鸡的存活率显著(P小于0.05)高于未用药或未接种疫苗且接触过病原体的火鸡。通过与带菌者接触并在饮用水中添加多杀巴斯德氏菌使火鸡接触病原体。证实了病原体可通过水从带菌者传播给受体。在引入带菌者一周后,从接受低剂量药物治疗的受体火鸡口腔中分离出了多杀巴斯德氏菌。