Leis M T, Hernández E, Maya D, Garza-Morales S, García-Cavazos R, Díaz-Caceres A C
Instituto Nacional de Perinatología, México, D.F.
Ginecol Obstet Mex. 1996 Apr;64:154-60.
The objective was to make the confirmation-exclusion diagnosis of fetal hydrocephaly, to study its etiology and identify associated anomalies. 67 cases with suspected fetal hydrocephaly were studied at 30 weeks of mean gestational age. Serial studies of ultrasonography, TORCH serology and fetal karyotype were made. Postnatal correlation was made. 14 cases were not confirm and 53 were. 6 cases (11.3%) were classified as isolated hydrocephaly and 47 (88.7%) with associated anomalies. In this group, 15 with only intracranial anomalies and 32 intracranial and extracranial anomalies. All chromosomic anomalies were found in this latter group. Proved in all the cases of hydrocephaly and most of its associated anomalies were documented. Fetal hydrocephaly can be accurately diagnosed with the technology presently available. The diagnosis of associated anomalies is more difficult to obtain, but can be reached using serial studies and multidisciplinary approach.
目的是对胎儿脑积水进行确诊-排除诊断,研究其病因并识别相关异常。对平均孕周30周的67例疑似胎儿脑积水病例进行了研究。进行了超声、TORCH血清学和胎儿核型的系列研究。并进行了产后相关性分析。14例未确诊,53例确诊。6例(11.3%)被归类为孤立性脑积水,47例(88.7%)伴有相关异常。在这一组中,15例仅有颅内异常,32例有颅内和颅外异常。所有染色体异常均在后者中发现。所有脑积水病例均得到证实,其大多数相关异常也有记录。目前可用的技术能够准确诊断胎儿脑积水。相关异常的诊断更难获得,但通过系列研究和多学科方法可以实现。