Krishna A
Department of Zoology, Banaras Hindu University, Varanasi, India.
J Reprod Fertil. 1996 Mar;106(2):207-11. doi: 10.1530/jrf.0.1060207.
The steroid hormone profile of Scotophilus heathi, and Indian tropical vespertilionid bat, was studied, with special reference to the period of delayed ovulation. The results show unusually high concentrations of circulating androstenedione and testosterone during the first half of the period of delayed ovulation, whereas the concentrations of progesterone and oestradiol were relatively low during this period. Androstenedione, testosterone and oestradiol concentrations were high during the period of ovarian recrudescence (October-November). The oestradiol concentration increased, whereas androstenedione and testosterone declined significantly, before ovulation. Studies in vitro showed that the ovary secrets more androstenedione and testosterone than does the adrenal. A histological study showed that a major part of the ovary of S. heathi was occupied by hypertrophied interstitial cells. An immunocytochemical study showed ovarian thecal interstitial cells as the major site of high androgen synthesis in the ovary. During the period of delayed ovulation the bat ovaries thus resemble the ovaries from women with polycystic ovaries in which abnormally high androgen secretion from hypertrophied interstitial cells prevent ovulation.
对印度热带蝙蝠褐扁颅蝠（Scotophilus heathi）的类固醇激素谱进行了研究，特别关注延迟排卵期。结果显示，在延迟排卵期的前半段，循环中的雄烯二酮和睾酮浓度异常高，而在此期间孕酮和雌二醇的浓度相对较低。在卵巢复壮期（10月至11月），雄烯二酮、睾酮和雌二醇浓度较高。排卵前，雌二醇浓度升高，而雄烯二酮和睾酮显著下降。体外研究表明，卵巢分泌的雄烯二酮和睾酮比肾上腺多。组织学研究显示，褐扁颅蝠卵巢的大部分被肥大的间质细胞占据。免疫细胞化学研究表明，卵巢的卵泡膜间质细胞是卵巢中雄激素高合成的主要部位。因此，在延迟排卵期，蝙蝠卵巢类似于多囊卵巢女性的卵巢，其中肥大的间质细胞异常高分泌雄激素会阻止排卵。
