Krishna A
Department of Zoology, Banaras Hindu University, Varanasi, India.
Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1997 Jan;116(1):97-101. doi: 10.1016/s0742-8413(96)00142-9.
Observations on body weight, circulating androstenedione concentrations and morphology of ovarian stroma were made in Scotophilus heathi during the period of delayed ovulation to make a comparison with polycystic ovarian syndrome in women. Body weight of bats increased from a level of 31.00 +/- 0.30 g in August and reached a peak of 45.00 +/- 0.46 g in November. This increase in body weight was due to accumulation of adipose tissue. The body weight declined gradually from December onwards and finally reached a basal level in March. The circulating androstenedione concentration showed a gradual increase from 36.80 +/- 15.54 ng/ml in August and reached a peak level of 220.50 +/- 50.10 ng/ml in November. Androstenedione concentration reached the lowest level in the March, just before ovulation. Morphological study showed extensive distribution of luteinized stromal cells or interstitial cells (ICs). Morphometric study showed that during the period of ovulatory delay, more than 75% area of the ovary was occupied by the ICs. Hyperandrogenism, anovulation, obesity (fat deposition) and stromal hyperthecosis present during delayed ovulation in S. heathi may serve as an experimental model for some aspects of the polycystic ovarian condition in women.
在延迟排卵期间，对印度假吸血蝠的体重、循环中的雄烯二酮浓度和卵巢基质形态进行了观察，以便与女性多囊卵巢综合征进行比较。蝙蝠的体重从8月的31.00±0.30克增加到11月的峰值45.00±0.46克。体重的增加是由于脂肪组织的积累。从12月起体重逐渐下降，最终在3月达到基础水平。循环中的雄烯二酮浓度从8月的36.80±15.54纳克/毫升逐渐增加，在11月达到峰值220.50±50.10纳克/毫升。雄烯二酮浓度在3月排卵前达到最低水平。形态学研究显示黄体化基质细胞或间质细胞（ICs）广泛分布。形态计量学研究表明，在排卵延迟期间，超过75%的卵巢面积被ICs占据。印度假吸血蝠排卵延迟期间出现的高雄激素血症、无排卵、肥胖（脂肪沉积）和基质泡膜细胞增生，可能作为女性多囊卵巢状况某些方面的实验模型。
