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不同治疗下慢性阻塞性肺疾病患者支气管黏液中的“分泌型 IgA 成分复合物”(作者译)

[The "IgA secretory component complex" in bronchial mucus in patients with chronic obstructive lung disease under different therapy (author's transl)].

作者信息

Rasche B, Curschmann P

出版信息

Respiration. 1979;37(2):97-108. doi: 10.1159/000194013.

Abstract

The concentration of "IgA secretory component complex" in the bronchial mucus was measured under different therapeutical influences. The "IgA secretory component complex" is a most important factor of the exogenous immunodefense. The formation of the "IgA secretory component complex" was independent from the age of the patients and from the intensity of their airway obstruction. Therapy with glucocorticosteroids and antibiotics had no certain influence on the formation of the immunocomplex. We did not find any certain influence of gammaglobulin therapy in adult patients with chronic airway obstruction, neither on the "IgA secretory component complex" nor on the immunoglobulin G, A and M. Furthermore, the clinical course of the disease was not influence by this therapy.

摘要

在不同治疗影响下,对支气管黏液中“分泌型IgA复合物”的浓度进行了测量。“分泌型IgA复合物”是外源性免疫防御的一个最重要因素。“分泌型IgA复合物”的形成与患者年龄及气道阻塞程度无关。糖皮质激素和抗生素治疗对免疫复合物的形成没有明确影响。我们未发现丙种球蛋白治疗对成年慢性气道阻塞患者有任何明确影响,对“分泌型IgA复合物”以及免疫球蛋白G、A和M均无影响。此外,该治疗对疾病的临床病程也无影响。

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