Netzer P, Lazarevic V, Hammer B
Abteilung für Gastroenterologie, Kantonsspital St. Gallen.
Schweiz Med Wochenschr Suppl. 1996;79:58S-63S.
An association between venous thrombosis and cancer was first suggested by Armand Trousseau in 1865 and subsequently confirmed by a number of studies. It was therefore concluded that laboratory tests, chest radiograph and abdominal ultrasonography should be routinely performed on all patients with deep venous thrombosis. The aim of our retrospective study was to detect the clinical relevance of abdominal ultrasonography findings, especially tumors, in patients with deep venous thrombosis of the lower extremities. All patients with deep venous thrombosis hospitalized between 1990 and 1994 in the department of internal medicine of our hospital were registered. Only patients were included in the study who (1) underwent abdominal ultrasonography in our department; (2) had confirmed acute deep venous thrombosis; (3) had no known malignancy. Malignancies which appeared after hospital stay were detected by telephone inquiry among patients and general practitioners in February 1995. Of the 371 patients with deep venous thrombosis 104 were included in the study. We found abnormal ultrasound findings in 68 patients (65%), but only in 23 patients were the findings of clinical relevance, in 12 of whom (12%) there was a connection with deep venous thrombosis. Ultrasound detected 3 malignancies (3%). The overall rate of newly detected malignancies was 10 (10%), of which 6 were detected during hospitalization and 4 afterwards. Based on these results we can recommend routine performance of abdominal ultrasonography on patients with deep venous thrombosis. A literature overview is given.
1865年,阿尔芒·特鲁索首次提出静脉血栓形成与癌症之间存在关联,随后多项研究证实了这一点。因此得出结论,应对所有深静脉血栓形成患者常规进行实验室检查、胸部X光检查和腹部超声检查。我们这项回顾性研究的目的是检测腹部超声检查结果,尤其是肿瘤,在下肢深静脉血栓形成患者中的临床相关性。对1990年至1994年间在我院内科住院的所有深静脉血栓形成患者进行了登记。纳入研究的患者需满足以下条件:(1)在我院接受腹部超声检查;(2)已确诊为急性深静脉血栓形成;(3)无已知恶性肿瘤。1995年2月通过对患者和全科医生进行电话询问,发现了住院后出现的恶性肿瘤。在371例深静脉血栓形成患者中,104例纳入研究。我们发现68例患者(65%)超声检查结果异常,但只有23例结果具有临床相关性,其中12例(12%)与深静脉血栓形成有关。超声检查发现3例恶性肿瘤(3%)。新发现恶性肿瘤的总体发生率为10例(10%),其中6例在住院期间发现,4例在住院后发现。基于这些结果,我们建议对深静脉血栓形成患者常规进行腹部超声检查。并给出了文献综述。