Schulte J M, Atkinson W L, Suarez L, Pelosi J, Wood R, Haley C E, Rutenberg G W
Texas Department of Health, Austin, USA.
South Med J. 1996 Aug;89(8):793-7. doi: 10.1097/00007611-199608000-00007.
Inadequate immunization has been a major cause of epidemic measles, but risk factors for inadequate immunization are poorly characterized. By using measles data bases and computerized birth certificate files, we identified a retrospective cohort of 1,070 Texas-born children who were aged 15 months to 10 years when they had measles during the 1988 to 1991 epidemics. We used measles and birth certificate data, including prenatal care and demographic information, to determine immunization status and risk factors for inadequate measles immunization. Risk factors predicting lack of immunization in children with measles in stepwise logistic regression were black ethnicity, urban residence, poor prenatal care, preschool age, and an unknown father. Birth certificates contain information that can predict inadequate measles vaccination and should be evaluated prospectively.
免疫接种不足一直是麻疹流行的主要原因，但免疫接种不足的风险因素却鲜为人知。通过使用麻疹数据库和计算机化的出生证明文件，我们确定了一个回顾性队列，其中包括1988年至1991年麻疹流行期间在得克萨斯州出生、患麻疹时年龄在15个月至10岁之间的1070名儿童。我们利用麻疹和出生证明数据，包括产前护理和人口统计学信息，来确定免疫接种状况以及麻疹免疫接种不足的风险因素。逐步逻辑回归分析显示，麻疹患儿未接种疫苗的预测风险因素包括黑人种族、城市居住、产前护理差、学龄前儿童以及父亲身份不明。出生证明包含的信息可以预测麻疹疫苗接种不足的情况，应进行前瞻性评估。
