Price J D, Fluker J L, Giles J H
Br J Vener Dis. 1977 Apr;53(2):113-4. doi: 10.1136/sti.53.2.113.
Talampicillin was effective in eradicating the causitive organism in uncomplicated gonorrhoea, with only four treatment failures (1-6%) in 245 patients seen at least once after treatment. Symptoms, such as discharge, were seen in 61 patients at some stage after treatment but 31 of these cases were clear after one or two follow-up visits. The anitbiotic was well tolerated. One patient developed a maculopapular rash, penicillin allergy was reported in two patients, and a generalised itch (possibly penicillin allergy) in one further patient. A total of 241 out of 245 (98%) cases had the urethral gonococcus successfully eradicated with talampicillin. Talampicillin given in single doses appears to be an extremely good choice of antibiotic in the treatment of uncomplicated gonorrhoea in men.
酞氨苄青霉素对根除单纯性淋病的病原体有效，在245例治疗后至少接受过一次复诊的患者中，仅有4例治疗失败（1 - 6%）。61例患者在治疗后的某个阶段出现了诸如分泌物增多等症状，但其中31例在一两次随访后症状消失。该抗生素耐受性良好。1例患者出现斑丘疹，2例报告有青霉素过敏，另有1例患者出现全身性瘙痒（可能为青霉素过敏）。245例中有241例（98%）的尿道淋球菌被酞氨苄青霉素成功根除。单剂量使用酞氨苄青霉素似乎是治疗男性单纯性淋病的极佳抗生素选择。
