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[儿童寄宿学校学生感染乙型和丙型肝炎病毒的风险]

[The risk of becoming infected with hepatitis B and C viruses in the pupils of children's boarding schools].

作者信息

Schastnyĭ E I, Muliar I S, Kuzin S N, Sharlaĭ M M, Sapego Zh K, Denisenko Iu T, Mikhal'chuk M S, Shakhgil'dian I V

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1996 Mar-Apr(2):29-32.

PMID:8701650
Abstract

The risk of contamination of 487 inmates of 5 boarding schools at northwestern Ukraine with hepatitis B (HB) and hepatitis C (HC) viruses was analyzed and the role of some factors facilitating the spread of these infections among the inmates of such schools was shown. In 28.3 +/- 2.2% of the inmates the presence of HB markers was detected, while these markers occurred only in 7.2 +/- 1.9% of children attending open schools. During the survey of the child population the presence of HB markers was detected in 8.0 +/- 1.1%, which was significantly lower than among the inmates of boarding schools (p < 0.001). Among such markers, HBsAg was detected in 8.3 +/- 0.5% of the inmates and in 1.6 +/- 0.5% of other children living in the area. Among inmates with CNS pathology the sum of markers was significantly higher than in inmates without such pathology (52.9 +/- 3.8%). The occurrence of the markers was shown to depend on the duration of staying in a boarding school and on the presence of the source of infection in the collective. Anti-HCV were detected in 1.4 +2- 0.6% of the inmates of boarding schools and in 0.5 +/- 0.3% of the whole child population.

摘要

对乌克兰西北部5所寄宿学校的487名学生感染乙型肝炎(HB)和丙型肝炎(HC)病毒的风险进行了分析,并揭示了一些促进这些感染在这类学校学生中传播的因素所起的作用。在28.3±2.2%的学生中检测到HB标志物,而这些标志物仅在7.2±1.9%的走读学校儿童中出现。在对儿童群体的调查中,8.0±1.1%的儿童检测到HB标志物,这显著低于寄宿学校学生(p<0.001)。在这些标志物中,8.3±0.5%的寄宿学校学生和1.6±0.5%的该地区其他儿童检测到HBsAg。患有中枢神经系统疾病的学生中标志物的总和显著高于没有此类疾病的学生(52.9±3.8%)。结果表明,标志物的出现取决于在寄宿学校的停留时间以及集体中感染源的存在情况。在1.4±0.6%的寄宿学校学生和0.5±0.3%的全体儿童中检测到抗HCV。

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