[The effect of an experimental staphylococcal infection on the morphofunctional characteristics of tissue basophils and mast cells].

In the process of staphylococcal infection in mice an increase in the number and functional activity of peritoneal, mesenterial and dermal basophils occurs. The preliminary activation of tissue basophils with equine serum albumin has favorable influence on the course of the infectious process, enhances the reaction of mast cells and phagocytes on the causative agent. The role played by tissue basophils in anti-infectious protection may be linked with the increased secretion of histamine producing a stimulating effect on the phagocytic mechanism of immunity.