Repceková D, Mikulaj L
Endokrinologie. 1977 Feb;69(1):115-8.
In young, adult male volunteers Leydig cell function tests were performed consisting of i.m. administration of 1500, 3000 or 4500 IU of HCG on days 1, 2 and 3 and plasma testosterone determination by radioimmunoassay. The stimulatory effect of HCG known from the literature is reconfirmed. However, no difference between the effect of the three dosage levels was found and the first significant effect of HCG was observed 24 h after its first application. Testosterone levels on day 3 and 4 are higher but not different from each other. A depression of plasma testosterone after treatment with an anabolic steroid (1alpha, 17alpha-dimethyl-5alpha-androstan-17-ol-3-one) 20 mg daily for 14 days is described. Reactivity to HCG was sustained in these subjects, but testosterone response to HCG was diminished at all investigated time intervals.
在年轻成年男性志愿者中进行了睾丸间质细胞功能测试，测试内容包括在第1、2和3天肌肉注射1500、3000或4500国际单位的人绒毛膜促性腺激素（HCG），并通过放射免疫测定法测定血浆睾酮水平。文献中已知的HCG的刺激作用得到再次证实。然而，未发现三种剂量水平的效果之间存在差异，且在首次应用HCG后24小时观察到其首个显著效果。第3天和第4天的睾酮水平较高，但彼此无差异。描述了在用合成代谢类固醇（1α，17α-二甲基-5α-雄甾烷-17-醇-3-酮）每天20毫克治疗14天后血浆睾酮的降低情况。这些受试者对HCG的反应性持续存在，但在所有研究的时间间隔内，对HCG的睾酮反应均减弱。
