Ambani L M, Jhung J W, Edelstein L M, Van Woert M H
Experientia. 1977 Mar 15;33(3):296-8. doi: 10.1007/BF02002788.
Melanin pigment in liver and heart tissue, obtained at autopsy from patients, was isolated and quantified. The quantity of melanin extracted was directly proportional to lipofuscin granule counts. Infrared and electron spin resonance spectographs of the isolated pigments from liver and heart showed absorption characteristics identical to those of known melanins. The pigment was absent in fetal and neonatal life, increased in brown atrophy of the heart and liver, and diminished in livers with fatty metamorphosis.
从尸检患者的肝脏和心脏组织中分离并定量了黑色素。提取的黑色素量与脂褐素颗粒计数直接成正比。从肝脏和心脏分离出的色素的红外光谱和电子自旋共振光谱显示出与已知黑色素相同的吸收特征。该色素在胎儿和新生儿期不存在，在心脏和肝脏的褐色萎缩中增加，而在发生脂肪变性的肝脏中减少。
