Madore F, Lazarus J M, Brady H R
J Am Soc Nephrol. 1996 Mar;7(3):367-86. doi: 10.1681/ASN.V73367.
Plasma exchange has been used extensively for over 2 1/2 decades to treat a variety of renal diseases. In this article, the scientific rationale for therapeutic plasma exchange in primary and secondary glomerulonephritis, thrombotic thrombocytopenic purpura and hemolytic uremic syndrome, myeloma cast nephropathy, and allograft rejection are reviewed. The clinical studies that evaluate its efficacy are summarized, with special emphasis on the results of randomized controlled trials, when available. Consensus plasma exchange regimens are presented for diseases in which there is evidence to support its use.
在超过25年的时间里，血浆置换已被广泛用于治疗多种肾脏疾病。本文回顾了在原发性和继发性肾小球肾炎、血栓性血小板减少性紫癜和溶血尿毒综合征、骨髓瘤管型肾病以及同种异体移植排斥反应中进行治疗性血浆置换的科学依据。总结了评估其疗效的临床研究，特别强调了随机对照试验的结果（如有）。针对有证据支持使用血浆置换的疾病，给出了共识性的血浆置换方案。
