[The effect of antidepressants on the catecholamine content of the rat hypothalamus and adrenals].

Chronic administration of depressants of various classes in rats and a single administration of reserpine result in changes in catecholamine exchange in both hypothalamus and adrenal glands. Antidepressants prevent from a sharp decrease in level of hypothalamic dofamine, induced with reserpine. The importance of central dofaminergic mechanisms for specific effect of compounds is emphasized.