Gorbonosov I V, Semenov F V
Eksp Klin Farmakol. 1996 Jan-Feb;59(1):71-3.
A method for objective evaluation of analgetic activity of drugs is proposed. The method consists in measuring changes in skin galvanic potential response to swallowing prior to and after administration of the drug to the patients within 2-3 days after tonsillectomy. The pain in the throat is of swallowing-induced character and thus results in orientation response which can be detected via changes in skin potential. The more the intensity of the pain the greater the response. The method is used in studying the analgetic effect of benzofurocain.
提出了一种客观评估药物镇痛活性的方法。该方法包括在扁桃体切除术后2至3天内，测量患者服用药物前后吞咽时皮肤电流电位反应的变化。喉咙疼痛具有吞咽诱发的特征，因此会导致定向反应，可通过皮肤电位变化检测到。疼痛强度越大，反应越大。该方法用于研究苯佐卡因的镇痛效果。
