Mitchell D, Rojiani A M, Richards D, Yachnis A T, Powell S Z
Department of Pathology, University of Florida College of Medicine, Gainesville 32610, USA.
Pediatr Pathol Lab Med. 1995 Nov-Dec;15(6):949-56. doi: 10.3109/15513819509027031.
A 30-week gestational age male fetus was found to have a congenital neoplasm involving the posterior cranial fossa, identified by fetal ultrasound examination in utero. Histological and immunohistochemical examination confirmed a diagnosis of primitive neuroectodermal tumor (PNET) of the posterior fossa, also referred to as medulloblastoma. Although PNETs have been well documented, there are relatively few reports of these occurring as congenital neoplasms. We present a case of an in utero, congenital PNET with a review of the literature and discussion of the criteria defining congenital tumors.
一名孕30周的男性胎儿经产前超声检查发现后颅窝有先天性肿瘤。组织学和免疫组化检查确诊为后颅窝原始神经外胚层肿瘤（PNET），也称为髓母细胞瘤。尽管PNET已有充分记载，但作为先天性肿瘤发生的报道相对较少。我们报告一例宫内先天性PNET病例，并复习文献及讨论先天性肿瘤的定义标准。
