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普通全科医生如何处理轻度高血压:对7个国家药品通报读者的一项调查。国际药品通报协会(ISDB)。

How informed general practitioners manage mild hypertension: a survey of readers of drug bulletins in 7 countries. International Society of Drug Bulletins (ISDB).

作者信息

Avanzini F, Tognoni G, Alli C, Colombo F, Herxheimer A

机构信息

Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy.

出版信息

Eur J Clin Pharmacol. 1996;49(6):445-50. doi: 10.1007/BF00195929.

Abstract

OBJECTIVE

To determine whether general practitioners (GP) who are readers of independent drug bulletins can be used as an international epidemiological observatory of the criteria adopted by "well informed" doctors in various countries in the management of mild hypertension.

DESIGN

Questionnaire study of GPs' diagnostic criteria for mild hypertension, routine investigation and management of patients with this diagnosis.

PARTICIPANTS

206 GPs readers of independent drug bulletins in 7 countries, comprising 95 known systematic readers of a local bulletin and 111 randomly selected regular subscribers.

MAIN OUTCOME MEASURES

Response rate to the questionnaire. Diagnostic criteria, routine investigations, and treatment used for patients with mild hypertension.

RESULTS

The study required two months for planning and implementation. Four countries out of eleven had a response rate < or = 50% and were excluded; the frequency of responses from other countries was 69%. The average diastolic blood pressure (DBP) considered diagnostic of mild hypertension range from 94 mm Hg (lower threshold) to 106 (upper threshold). A minority (17%) of GPs routinely request the minimum recommended laboratory tests to assess patients. GPs routinely advise non-drug measures before starting a drug. Most would not start drug treatment in patients without other risk factors and a DBP below 100 mmHg. The top first choice drugs were diuretics and beta-adrenoceptor blockers. Half of the doctors were able to quote some published guide to the management of mild hypertension, and 18% cited a relevant trial. Attitudes in diagnosing and treating mild hypertension differed widely between GPs and countries.

CONCLUSIONS

GP readers of drug bulletins can be used quickly and inexpensively to assess the extent to which recommended diagnostic and therapeutic practices are accepted by "well informed" doctors. The results suggest that attitudes in managing mild hypertension vary widely among GPs and countries and differ remarkably from the recommendations of published guidelines.

摘要

目的

确定阅读独立药物简报的全科医生(GP)是否可作为一个国际流行病学观察站,用于观察各国“消息灵通”的医生在轻度高血压管理中所采用标准的情况。

设计

对全科医生关于轻度高血压的诊断标准、对此诊断患者的常规检查及管理进行问卷调查研究。

参与者

来自7个国家的206名阅读独立药物简报的全科医生,包括95名已知的当地简报系统读者和111名随机选择的定期订阅者。

主要观察指标

问卷回复率。轻度高血压患者的诊断标准、常规检查及治疗方法。

结果

该研究的规划和实施耗时两个月。11个国家中有4个国家的回复率≤50%,被排除;其他国家的回复频率为69%。被认为可诊断轻度高血压的平均舒张压(DBP)范围为94毫米汞柱(下限)至106(上限)。少数(17%)全科医生会常规要求进行评估患者所需的最低推荐实验室检查。全科医生在开始用药前通常会建议采取非药物措施。大多数人不会对没有其他危险因素且舒张压低于100毫米汞柱的患者开始药物治疗。首选药物是利尿剂和β肾上腺素能受体阻滞剂。一半的医生能够引用一些已发表的轻度高血压管理指南,18%的医生引用了相关试验。全科医生之间以及不同国家在诊断和治疗轻度高血压方面的态度差异很大。

结论

药物简报的全科医生读者可被快速且低成本地用于评估“消息灵通”的医生对推荐的诊断和治疗方法的接受程度。结果表明,全科医生之间以及不同国家在轻度高血压管理方面的态度差异很大,且与已发表指南的建议显著不同。

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