蛋白质含量对淋巴液和血浆电解质成分的影响。

Influence of protein content upon the electrolyte composition of lymph and plasma.

作者信息

O'Morchoe C C, Holmes M J, Pinter G G, Jarosz H

出版信息

Lymphology. 1977 Mar;10(1):32-5.

Abstract

The concentration of Na+ and Cl' is higher in renal hilar lymph (HL) than in arterial (P) or renal venous plasma or thoracic duct lymph (TDL). The purpose of the present study was to test the theory that this is the consequence of differences in protein content of lymph and plasma rather than a reflection of renal function. Samples of P, HL and TDL were obtained from dogs and analysed for Na+, Cl', K+ and Ca++. The samples were then centrifuged through an ultrafiltration membrane to remove the protein and reanalysed for electrolyte content. Ca++ concentrations were reduced by 30-40% in the (protein-free) filtrate. This was attributed to protein binding. Na+ and Cl' concentrations were raised minimally (2.0 mEq/L and 5.0 mEq/L respectively) in protein-free filtrate of plasma, but not in protein-free filtrate of lymph. It was concluded that the relative protein concentration in lymph and plasma are not an important influence on Na+ and Cl' concentrations.

摘要

肾门淋巴（HL）中Na⁺和Cl⁻的浓度高于动脉血（P）、肾静脉血浆或胸导管淋巴（TDL）。本研究的目的是验证这一理论：这是淋巴和血浆中蛋白质含量差异的结果，而非肾功能的反映。从狗身上获取P、HL和TDL的样本，并分析其中的Na⁺、Cl⁻、K⁺和Ca²⁺。然后将样本通过超滤膜离心以去除蛋白质，并重新分析电解质含量。（无蛋白质的）滤液中Ca²⁺浓度降低了30 - 40%。这归因于蛋白质结合。血浆无蛋白质滤液中Na⁺和Cl⁻浓度略有升高（分别为2.0 mEq/L和5.0 mEq/L），但淋巴无蛋白质滤液中则没有。得出的结论是，淋巴和血浆中的相对蛋白质浓度对Na⁺和Cl⁻浓度并非重要影响因素。