Zhuang L, Zhu W
Department of Dermatology, First Affiliated Hospital of Nanjing Medical University, People's Republic of China.
J Dermatol. 1996 Jun;23(6):415-8. doi: 10.1111/j.1346-8138.1996.tb04044.x.
The clinical and histopathological findings in a case of inflammatory linear verrucose epidermal nevus coexisting with lichen amyloidosus are presented. A 33-year-old woman had had linear verrucose lesions which were histopathologically compatible with ILVEN, and with which no amyloid deposits were associated, on her left lower leg for 30 years. She had noticed keratotic papules around the verrucose lesions on the left leg for the last 3 years. Histopathology of these papules revealed amyloid deposits in the upper dermis under the hyperkeratotic and acanthotic epidermis. Topical application of DMSO liniment with dexamethasone successfully treated the ILVEN. This remission of both lesions and itching also alleviated the keratotic papules on the left leg.
本文报告了一例炎症性线状疣状表皮痣合并苔藓样淀粉样变的临床及组织病理学表现。一名33岁女性，左小腿出现线状疣状皮损30年，组织病理学检查符合炎症性线状疣状表皮痣（ILVEN），且无淀粉样沉积。在过去3年中，她注意到左腿疣状皮损周围出现角化性丘疹。这些丘疹的组织病理学检查显示，在角化过度和棘层肥厚的表皮下方的真皮上层有淀粉样沉积。外用含地塞米松的二甲亚砜搽剂成功治疗了ILVEN。两种皮损及瘙痒症状的缓解也减轻了左腿的角化性丘疹。
