Stein P D, Henry J W, Gottschalk A
Henry Ford Heart and Vascular Institute, Detroit, Michigan 48202-2691, USA.
J Nucl Med. 1996 Aug;37(8):1313-6.
The purpose of this investigation was to assess the diagnostic value of 1 to 3 versus > 3 small subsegmental defects on perfusion lung scans of patients with suspected acute pulmonary embolism (PE).
Data from the Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED) were evaluated from patients with suspected acute PE. Angiograms, follow-up data and outcome classifications were used to determine PE status. The perfusion scan of included patients showed only small subsegmental defects ( < 25% of a segment) in the presence of a regionally normal chest radiograph. Findings on the ventilation scan were irrelevant.
The positive predictive value for PE of perfusion lung scans with 1-3 small subsegmental defects was 1% to 3%, depending on the group analyzed. The positive predictive value for the PE of perfusion lung scans with > 3 small subsegmental defects was 11% to 17% depending on the group analyzed.
Perfusion lung scans with 1-3 small subsegmental defects satisfy the criterion for a very low probability ( < 10% positive predictive value) for PE and perfusion lung scans with > 3 small subsegmental defects satisfy the criteria for a low probability ( < 20% positive predictive value) for PE.
本研究的目的是评估在疑似急性肺栓塞（PE）患者的灌注肺扫描中，1至3个与超过3个小亚段缺损的诊断价值。
对来自肺栓塞诊断前瞻性研究（PIOPED）中疑似急性PE患者的数据进行评估。血管造影、随访数据和结果分类用于确定PE状态。纳入患者的灌注扫描在胸部X线片区域正常的情况下仅显示小亚段缺损（<一个肺段的25%）。通气扫描结果无关紧要。
根据分析的组不同，有1至3个小亚段缺损的灌注肺扫描对PE的阳性预测值为1%至3%。根据分析的组不同，有超过3个小亚段缺损的灌注肺扫描对PE的阳性预测值为11%至17%。
有1至3个小亚段缺损的灌注肺扫描符合PE极低概率（阳性预测值<10%）的标准，有超过3个小亚段缺损的灌注肺扫描符合PE低概率（阳性预测值<20%）的标准。
