Zanotto P M, Gibbs M J, Gould E A, Holmes E C
Natural Environment Research Council, Institute of Virology and Environmental Microbiology, Oxford, United Kingdom.
J Virol. 1996 Sep;70(9):6083-96. doi: 10.1128/JVI.70.9.6083-6096.1996.
In order to assess the validity of classifications of RNA viruses, published alignments and phylogenies of RNA-dependent RNA and DNA polymerase sequences were reevaluated by a Monte Carlo randomization procedure, bootstrap resampling, and phylogenetic signal analysis. Although clear relationships between some viral taxa were identified, overall the sequence similarities and phylogenetic signals were insufficient to support many of the proposed evolutionary groupings of RNA viruses. Likewise, no support for the common ancestry of RNA-dependent RNA polymerases and reverse transcriptases was found.
为了评估RNA病毒分类的有效性,通过蒙特卡洛随机化程序、自展重抽样和系统发育信号分析,对已发表的RNA依赖的RNA聚合酶和DNA聚合酶序列的比对和系统发育进行了重新评估。尽管确定了一些病毒分类群之间的明确关系,但总体而言,序列相似性和系统发育信号不足以支持许多提出的RNA病毒进化分组。同样,未发现支持RNA依赖的RNA聚合酶和逆转录酶共同祖先的证据。