卵胞浆内单精子注射：一种治疗严重少精子症的方法。
Intracytoplasmic sperm injection: a treatment for extreme oligospermia.
作者信息
Gil-Salom M, Minguez Y, Rubio C, Ruiz A, Remohi J, Pellicer A
机构信息
Instituto Valenciano de Infertilidad, University of Valencia Medical School, Spain.
出版信息
J Urol. 1996 Sep;156(3):1001-4. doi: 10.1016/s0022-5347(01)65685-4.
PURPOSE
We evaluated the efficacy of intracytoplasmic sperm injection in patients with extreme oligospermia.
MATERIALS AND METHODS
A total of 67 intracytoplasmic sperm injection cycles was attempted in 58 infertile couples in which the husbands had extreme oligospermia (less than 100,000 spermatozoa per ml. ejaculate).
RESULTS
Fertilization was achieved in 65 of 67 cycles. Mean fertilization rate per cycle was 66.4%. A total of 18 clinical pregnancies was obtained, for a pregnancy rate of 26.8% per started cycle. There were 4 miscarriages and 8 live births from 5 deliveries. Nine pregnancies are ongoing.
CONCLUSIONS
Intracytoplasmic sperm injection in patients with extreme oligospermia is associated with high fertilization rates and offers the chance of pregnancy to these otherwise intractably infertile couples.
目的
我们评估了卵胞浆内单精子注射对严重少精子症患者的疗效。
材料与方法
对58对不育夫妇共尝试了67个卵胞浆内单精子注射周期，这些夫妇的丈夫患有严重少精子症（每毫升精液中精子少于100,000个）。
结果
67个周期中有65个实现了受精。每个周期的平均受精率为66.4%。共获得18例临床妊娠，起始周期的妊娠率为26.8%。5次分娩中有4例流产，8例活产。9例妊娠仍在继续。
结论
严重少精子症患者进行卵胞浆内单精子注射受精率高，为这些原本难以治疗的不育夫妇提供了妊娠机会。
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