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卵胞浆内单精子注射:治疗其他方法难以治愈的梗阻性无精子症的有效方法。

Intracytoplasmic testicular sperm injection: an effective treatment for otherwise intractable obstructive azoospermia.

作者信息

Gil-Salom M, Minguez Y, Rubio C, Remohi J, Pellicer A

机构信息

Instituto Valenciano de Infertilidad, Valencia, Spain.

出版信息

J Urol. 1995 Dec;154(6):2074-7. doi: 10.1016/s0022-5347(01)66698-9.

DOI:10.1016/s0022-5347(01)66698-9
PMID:7500461
Abstract

PURPOSE

We evaluated the efficacy of intracytoplasmic sperm injection with testicular spermatozoa.

MATERIALS AND METHODS

Intracytoplasmic sperm injection was performed with spermatozoa obtained from testicular biopsy specimens in 15 patients with obstructive azoospermia, in whom standard microsurgical procedures were not feasible or had previously failed.

RESULTS

Fertilization was achieved in 14 of 15 cycles. Mean fertilization rate per cycle was 63.6%. Four clinical pregnancies occurred, for a pregnancy rate of 26.7% per started cycle and 28.6% per transfer.

CONCLUSIONS

Intracytoplasmic testicular sperm injection is followed by high fertilization rates, and offers the chance of a pregnancy to otherwise intractably infertile couples with obstructive azoospermia.

摘要

目的

我们评估了睾丸精子胞浆内注射的疗效。

材料与方法

对15例梗阻性无精子症患者进行了睾丸精子胞浆内注射,这些患者无法进行标准显微外科手术或此前手术失败。

结果

15个周期中有14个实现了受精。每个周期的平均受精率为63.6%。发生了4例临床妊娠,起始周期的妊娠率为26.7%,每次移植的妊娠率为28.6%。

结论

睾丸精子胞浆内注射后受精率高,为患有梗阻性无精子症的顽固性不育夫妇提供了妊娠机会。

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Intracytoplasmic testicular sperm injection: an effective treatment for otherwise intractable obstructive azoospermia.卵胞浆内单精子注射:治疗其他方法难以治愈的梗阻性无精子症的有效方法。
J Urol. 1995 Dec;154(6):2074-7. doi: 10.1016/s0022-5347(01)66698-9.
2
Testicular sperm extraction and intracytoplasmic sperm injection: a chance of fertility in nonobstructive azoospermia.睾丸精子提取术及卵胞浆内单精子注射术:非梗阻性无精子症患者的生育希望
J Urol. 1998 Dec;160(6 Pt 1):2063-7.
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Intracytoplasmic sperm injection: a treatment for extreme oligospermia.卵胞浆内单精子注射:一种治疗严重少精子症的方法。
J Urol. 1996 Sep;156(3):1001-4. doi: 10.1016/s0022-5347(01)65685-4.
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Outcome of in vitro fertilization and intracytoplasmic injection of epididymal and testicular sperm obtained from patients with obstructive and nonobstructive azoospermia.梗阻性和非梗阻性无精子症患者附睾和睾丸精子体外受精及卵胞浆内单精子注射的结局
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Testicular sperm extraction with intracytoplasmic sperm injection for nonobstructive azoospermia.睾丸精子提取联合卵胞浆内单精子注射治疗非梗阻性无精子症
Urology. 1997 Mar;49(3):435-40. doi: 10.1016/S0090-4295(97)00032-0.
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Efficacy of intracytoplasmic sperm injection using testicular spermatozoa.使用睾丸精子进行卵胞浆内单精子注射的疗效
Hum Reprod. 1995 Dec;10(12):3166-70. doi: 10.1093/oxfordjournals.humrep.a135880.
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Quality of cryopreserved testicular sperm in patients with obstructive and nonobstructive azoospermia.梗阻性和非梗阻性无精子症患者冷冻保存的睾丸精子质量
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High implantation and pregnancy rates with testicular sperm extraction and intracytoplasmic sperm injection in obstructive and non-obstructive azoospermia.在梗阻性和非梗阻性无精子症患者中,睾丸精子提取术联合卵胞浆内单精子注射术具有较高的着床率和妊娠率。
Hum Reprod. 1996 Mar;11(3):673-6. doi: 10.1093/humrep/11.3.673.
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Epididymal and testicular sperm for intracytoplasmic sperm injection in the treatment of obstructive azoospermia.附睾精子和睾丸精子用于卵胞浆内单精子注射治疗梗阻性无精子症。
Acta Obstet Gynecol Scand. 1997 Feb;76(2):135-9. doi: 10.3109/00016349709050069.
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Testicular needle biopsy, open biopsy, epididymal aspiration and intracytoplasmic sperm injection in obstructive azoospermia.梗阻性无精子症的睾丸针吸活检、开放活检、附睾抽吸及卵胞浆内单精子注射
Hum Reprod. 1995 Oct;10(10):2595-9.

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The potential use of maturation in vitro of human oocytes in low responder patients.人类卵母细胞体外成熟技术在低反应患者中的潜在应用。
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