Gardner S M, Wolf J S, Nakada S Y, Moon Y T, Figenshau R S, Pearle M S, Soble J J, Humphrey P A, Clayman R V
Department of Surgery, Washington University, St. Louis, Missouri 63110, USA.
J Urol. 1996 Sep;156(3):1160-3.
The duration of stenting after endoureterotomy is a controversial issue. An even more basic question, however, is whether stent placement is needed at all. We performed a porcine study to address this question.
A unilateral midureteral stricture was created in 20 minipigs. Six weeks later, 15 pigs underwent endoureterotomy. In 10 animals, a 7F ureteral stent was placed for 1 week. Five pigs remained unstented. Three months later, all 20 ureters were studied radiographically and were harvested.
Three of 5 control animals and 2 of 10 stented animals has strictures. In the unstented study group, all 5 animals had a nonobstructing dilation at the site of endoureterotomy. This was corroborated by a normal furosemide washout renal scan in all 3 animals so tested.
The result of unstented endoureterotomy in the porcine model suggests that, after endoureterotomy of secondary midureteral strictures, stenting may be unnecessary.
输尿管内切开术后支架置入的持续时间是一个有争议的问题。然而,一个更基本的问题是是否根本需要放置支架。我们进行了一项猪实验来解决这个问题。
在20只小型猪身上制造单侧输尿管中段狭窄。六周后,15只猪接受了输尿管内切开术。其中10只动物放置了7F输尿管支架1周。5只猪未放置支架。三个月后,对所有20条输尿管进行了影像学研究并将其切除。
5只对照动物中有3只,10只放置支架的动物中有2只出现狭窄。在未放置支架的研究组中,所有5只动物在输尿管内切开术部位均有非梗阻性扩张。所有3只接受此项测试的动物的速尿洗脱肾扫描结果均正常,证实了这一点。
猪模型中未放置支架的输尿管内切开术结果表明,继发于输尿管中段狭窄的输尿管内切开术后,可能无需放置支架。