Bogin E, Ziv G, Avidar J, Rivetz B, Gordin S, Saran A
Res Vet Sci. 1977 Mar;22(2):198-200.
The patterns of distribution of lactate dehydrogenase (LDH) isoenzymes were determined in normal and inflamed bovine udder tissues, in normal and mastitic milk-leucocytes and serum. LDH1 was the most common isoenzyme found in all the types of tissues examined, normal tissues contained the lowest proportions of LDH5 whereas the inflamed tissues and leucocytes from mastitic milk showed a higher proportion of LDH4 and LDH5. It seems that the origin of the elevated LDH in mastitic milk is the leucocytes and the parenchyma cells of the udder. The significance of the shift in the molecular forms of LDH isoenzymes is discussed in relation to possible alternations in energy metabolism in the inflamed bovine mammary gland.
在正常和发炎的牛乳房组织、正常和患乳腺炎乳中的白细胞及血清中，测定了乳酸脱氢酶（LDH）同工酶的分布模式。LDH1是在所检查的所有类型组织中最常见的同工酶，正常组织中LDH5的比例最低，而发炎组织和患乳腺炎乳中的白细胞显示出较高比例的LDH4和LDH5。乳腺炎乳中LDH升高的来源似乎是乳房的白细胞和实质细胞。结合发炎牛乳腺中能量代谢可能的变化，讨论了LDH同工酶分子形式转变的意义。
