不明原因的天冬氨酸转氨酶高活性（EC 2.6.1.1）：一例报告
Unexplained high activity of aspartate aminotransferase (EC 2.6.1.1): a case report.
作者信息
de Jonge N, Houwing A
机构信息
Department of Clinical Chemistry, Diagnostic Center SSDZ, Delft, Netherlands.
出版信息
Neth J Med. 1996 Jun;48(6):224-6. doi: 10.1016/0300-2977(95)00095-x.
PMID:8710043
Abstract
We report a case of unexplained and persistently elevated ASAT activity in serum. This appeared to be due to a macro-enzyme of ASAT, as was demonstrated by protein-A-Sepharose treatment of the serum sample. Although macro-ASAT seems to be clinically irrelevant, unexplained raised ASAT activity without acknowledgement of its macroenzyme nature may lead to unnecessary diagnostic procedures.
摘要
我们报告一例血清中天门冬氨酸氨基转移酶（ASAT）活性不明且持续升高的病例。血清样本经蛋白A-琼脂糖凝胶处理后表明，这种情况似乎是由ASAT的一种巨酶所致。尽管巨ASAT在临床上似乎无关紧要，但未认识到其巨酶性质而出现的不明原因ASAT活性升高可能会导致不必要的诊断程序。
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