Foust R T, O'Brien J F, Schiff E R
University of Miami School of Medicine, Florida.
Am J Gastroenterol. 1990 Jan;85(1):88-90.
Serum aspartate aminotransferase (AST) has rarely been reported to complex with immunoglobulins, resulting in abnormally elevated serum activity. A similar phenomenon occurs with serum amylase, resulting in the more common entity of macroamylasemia. AST macroenzyme formation can occur in the presence or absence of liver disease and, at times, can lead to a false suspicion of liver disease. We describe the abnormal liver histology found in a healthy patient with isolated AST elevation due to AST macroenzyme formation.
血清天冬氨酸氨基转移酶（AST）与免疫球蛋白形成复合物，导致血清活性异常升高的情况鲜有报道。血清淀粉酶也会出现类似现象，从而导致更为常见的巨淀粉酶血症。AST巨酶的形成可在有或无肝脏疾病的情况下发生，有时会导致对肝脏疾病的误诊。我们描述了一名健康患者因AST巨酶形成导致单纯AST升高时所发现的肝脏组织学异常。
