Phillips L H, Whisnant J P, Reagan T J
Stroke. 1977 May-Jun;8(3):392-5. doi: 10.1161/01.str.8.3.392.
Sudden death is defined as any death that occurs less than 24 hours after the onset of first symptoms. Strokes account for 10 to 20% of all sudden deaths. The records of all residents of Rochester, Minn., who had their first stroke during the period 1955 through 1969 were analyzed. Among 255 deaths caused by the first stroke, 52 were sudden. Twenty-six of the deaths were due to primary intracerebral hemorrhage, and 20 to primary subarachnoid hemorrhage. Only two of the sudden deaths were caused by infarction: one by pontine and cerebellar infarct and the second by a cortical infarct, which resulted in death from status epilepticus. Among the nine patients who died within 2 hours of the onset of symptoms, six had primary subarachnoid hemorrhage. Hypertension was noted in 23 of the 26 patients (88%) who died of primary intracerebral hemorrhage; 8 patients with primary intracerebral hemorrhage were on long-term oral anticoagulant therapy, and all 8 were hypertensive.
猝死定义为首发症状出现后24小时内发生的任何死亡。中风占所有猝死病例的10%至20%。对明尼苏达州罗切斯特市1955年至1969年期间首次中风的所有居民记录进行了分析。在255例由首次中风导致的死亡病例中,52例为猝死。26例死亡归因于原发性脑出血,20例归因于原发性蛛网膜下腔出血。猝死病例中仅有2例由梗死引起:1例为脑桥和小脑梗死,另1例为皮质梗死,后者导致癫痫持续状态死亡。在症状出现后2小时内死亡的9例患者中,6例患有原发性蛛网膜下腔出血。在26例死于原发性脑出血的患者中,23例(88%)有高血压;8例原发性脑出血患者接受长期口服抗凝治疗,且所有8例均患有高血压。