Kleckner H B, Giles H R, Corrigan J J
Am J Obstet Gynecol. 1977 Jun 1;128(3):235-8. doi: 10.1016/0002-9378(77)90614-7.
In this study of 136 women with pre-eclampsia, eclampsia, placenta previa, or abruptio placentae, 21 mothers were noted to have thrombocytopenia. Seventeen of the 21 were in the pre-eclampsia group. Of the 21 thrombocytopenic mothers, nine were associated with thrombocytopenia in the children, seven children had normal platelet counts, and five had no counts performed. Eight of the nine thrombocytopenic neonates were associated with pre-eclampsia in the mother, and five of these were not believed to have disseminated intravascular coagulation as the etiology of the platelet defect. The results suggest that thrombocytopenia is common in high-risk pregnancies in both the mother and the baby. However, the etiology of the platelet defect cannot be easily explained on the basis of a hypercoagulable state.
在这项针对136名患有先兆子痫、子痫、前置胎盘或胎盘早剥的女性的研究中，发现有21名母亲存在血小板减少症。这21名母亲中有17名属于先兆子痫组。在这21名血小板减少的母亲中，9名母亲的孩子也出现了血小板减少，7名孩子的血小板计数正常，5名孩子未进行血小板计数。9名血小板减少的新生儿中有8名与母亲的先兆子痫有关，其中5名被认为血小板缺陷的病因并非弥散性血管内凝血。结果表明，血小板减少症在高危妊娠的母亲和婴儿中都很常见。然而，基于高凝状态难以轻易解释血小板缺陷的病因。
