Mouna Kalavakuru, Doddagowda Shilpa Manigatta, Junjegowda Krishnappa, Krishnamurthy Latha
Student, Department of Pathology, Sri Devaraj Urs Medical College, Kolar, Karnataka, India.
Assistant Professor, Department of Pathology, Sri Devaraj Urs Medical College, Kolar, Karnataka, India.
J Clin Diagn Res. 2017 Jul;11(7):EC26-EC29. doi: 10.7860/JCDR/2017/29137.10303. Epub 2017 Jul 1.
Pregnancy is a physiological phenomenon. However, some women develop problems during pregnancy period, which puts both the mother's and the foetus health at risk. Hypertensive disorders of pregnancy are the type of the maternal diseases that can cause the most detrimental effects to the mother and foetus.
To determine the haematological parameters in neonates born to preeclamptic mothers.
It was a prospective case control study carried out on neonates born to preeclamptic mothers in our institute from March 2016 to November 2016. All the haematological parameters of the neonates were recorded and analyzed using SPSS 22.0 version software. Mean, Standard deviation, minimum and maximum values were calculated for continuous variables. The difference between the two groups was compared using independent student 't' test. The p-value <0.05 was considered as statistically significant.
About 120 mothers were included in the study out of which 60 were of study group and 60 of control group. Mean hemoglobin, PCV, red cell count, Mean Corpuscular Volume (MCV), reticulocyte count and nRBC were significantly increased p<0.001, whereas total leucocyte count, mean neutrophil count, absolute neutrophil count, lymphocyte count, platelet count were significantly decreased p<0.001 in babies born to preeclamptic mothers. No difference was found between the two groups in the Mean Corpuscular Haemoglobin (MCH) and Mean Corpuscular Haemoglobin Concentration (MCHC) value p(>0.05).
The babies born to preeclamptic mothers are more prone for development of prematurity, low birth weight, Intrauterine Growth Retardation (IUGR), sepsis, neutropenia, leucopenia, thrombocytopenia, increased RBC count, nRBC and reticulocyte count. Early haematological screening helps to decrease morbidity, improve growth, development and survival of the baby.
怀孕是一种生理现象。然而，一些女性在孕期会出现问题，这会危及母亲和胎儿的健康。妊娠期高血压疾病是对母亲和胎儿危害最大的一类孕产妇疾病。
确定子痫前期母亲所生新生儿的血液学参数。
这是一项前瞻性病例对照研究，于2016年3月至2016年11月在我院对患有子痫前期的母亲所生新生儿进行。记录所有新生儿的血液学参数，并使用SPSS 22.0版软件进行分析。计算连续变量的均值、标准差、最小值和最大值。两组间的差异采用独立样本t检验进行比较。p值<0.05被认为具有统计学意义。
该研究共纳入约120名母亲，其中60名为研究组，60名为对照组。子痫前期母亲所生婴儿的平均血红蛋白、红细胞压积、红细胞计数、平均红细胞体积（MCV）、网织红细胞计数和有核红细胞显著升高（p<0.001），而白细胞总数、平均中性粒细胞计数、绝对中性粒细胞计数、淋巴细胞计数、血小板计数显著降低（p<0.001）。两组间平均红细胞血红蛋白（MCH）和平均红细胞血红蛋白浓度（MCHC）值无差异（p>0.05）。
子痫前期母亲所生的婴儿更容易出现早产、低出生体重、宫内生长受限（IUGR）、败血症、中性粒细胞减少、白细胞减少、血小板减少、红细胞计数增加、有核红细胞和网织红细胞计数增加。早期血液学筛查有助于降低发病率，改善婴儿的生长、发育和存活率。
