Einhäupl K M, Masuhr F
Neurologische Klinik der Charité Berlin.
Ther Umsch. 1996 Jul;53(7):552-8.
Cerebral sinus and venous thrombosis account for less than 1% of all strokes, but diagnosis is often overlooked due to the variety of clinical syndromes and the variable clinical course. Underlying conditions do not significantly differ from those seen in extracerebral venous thrombosis. Conventional intra-arterial four-vessel angiography was long the only diagnostic technique for confirming diagnosis, but nowadays magnetic resonance imaging and angiography are sufficient in many cases. Full-dose heparin treatment is the therapy of choice and is performed even if an hemorrhagic infarct already exists. If treatment is initiated early, the mortality rate of nonseptic cerebral sinus and venous thrombosis is less than 10%. According to general rules of postthrombotic treatment, patients should be treated with oral anticoagulants for a period of at least three months.
脑窦和静脉血栓形成占所有中风的比例不到1%,但由于临床综合征的多样性和临床病程的多变性,诊断往往被忽视。其潜在病因与脑外静脉血栓形成所见的病因并无显著差异。长期以来,传统的动脉内四血管血管造影是确诊的唯一诊断技术,但如今在许多情况下,磁共振成像和血管造影就足够了。全剂量肝素治疗是首选治疗方法,即使已经存在出血性梗死也会进行治疗。如果早期开始治疗,非感染性脑窦和静脉血栓形成的死亡率低于10%。根据血栓形成后治疗的一般规则,患者应接受至少三个月的口服抗凝剂治疗。